Hydrazine → HCID 20435928, 화합물

HRID 1154032노트

반응식

HRID 1154032 반응식
[CH3:1][C:2]([CH2:13][CH2:14][O:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][O:17]1)([C:8](OCC)=[O:9])[C:3](OCC)=[O:4].[NH2:22][NH2:23]>>[CH3:1][C:2]1([CH2:13][CH2:14][O:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][O:17]2)[C:8](=[O:9])[NH:23][NH:22][C:3]1=[O:4]

참가 물질

3

반응물 2

HCID 9321HydrazineHCID 20435998HCID 20435998, 화합물

생성물 1

HCID 20435928HCID 20435928, 화합물수율 62%

실험 절차

A mixture of 120.8 g (0.4 mol) of diethyl 2-methyl-2-[2-(tetrahydro-2-pyranyloxy)ethyl]-propane-1,3-dioate and 150 ml of anhydrous hydrazine was heated under reflux for 64 hours. The excess hydrazine was removed by distillation and the residue was recrystallized from methanol to give 60.28 g (62%) of 4-methyl-4-[2-(tetrahydro-2-pyranyloxy)-ethyl]-pyrazolidine-3,5-dione having a melting point of 179°-180° C.

후처리

  1. temperaturewas heated
  2. temperatureunder reflux for 64 hours
  3. customThe excess hydrazine was removed by distillation
  4. customthe residue was recrystallized from methanol

출처 및 근거

ORD 기록
ord-6d1dba4ee100425ba9a53fd1dda0cf95
출처 데이터셋
uspto-grants-1984_12
특허 번호
US04487929

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