Chlorosulfonic acid → 2,4,6-Trimethoxybenzene-1-sulfonyl chloride
반응식
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([O:11][CH3:12])[CH:4]=1.[Cl:13][S:14](O)(=[O:16])=[O:15]>ClCCl>[CH3:12][O:11][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([O:9][CH3:10])[C:6]=1[S:14]([Cl:13])(=[O:16])=[O:15]참가 물질
4
실험 절차
In 500 ml of dichloromethane is dissolved 5.05 g of 1,3,5-trimethoxybenzene and the solution was cooled to -5°~-10° C. A solution of 6 ml of chlorosulfonic acid in 400 ml of dichloromethane was added dropwise, and the mixture was allowed to stand at room temperature. The reaction mixture was then treated as in Reference Example 1. The resulting product was crystallized from carbon tetrachloride and filtered. Yield 610 mg (6.3%), m.p. 126°-129° C.
후처리
- temperaturethe solution was cooled to -5°~-10° C
- customto stand at room temperature
- additionThe reaction mixture was then treated as in Reference Example 1
- customThe resulting product was crystallized from carbon tetrachloride
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-b3da34e3a0844fb0af586bf29621a65f
- 출처 데이터셋
- uspto-grants-1984_12
- 특허 번호
- US04487726
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