Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 1H-Purine, 8-(2,4-dimethoxyphenyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2,4-Dimethoxybenzoic acid | HCID 7052 | — |
| 반응물 | 4,5-Diaminopyrimidine | HCID 83703 | — |
| 생성물 | 1H-Purine, 8-(2,4-dimethoxyphenyl)- | HCID 3059912 | — |
반응 단계
A mixture of 5.5 g of 4,5-diaminopyrimidine and 10.9 g of 2,4-dimethoxy-benzoic acid was triturated in a mortar. The mixture was added to 100 ml of phosphorus oxychloride and refluxed for one hour. The phosphorus oxychloride was decomposed under stirring into water, and the solution obtained was neutralized with ammonia after filtration. The precipitated product was recrystallized from water and ethanol/cyclohexane (volume ratio of 1:3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04299834 |
| 출처 데이터셋 | uspto-grants-1981_11 |
| ORD ID | ord-6a90d463b66a4dcfa829660cb11e8926 |
| 출처 메모 | uspto-grants-1981_11 |