Trimethylsilyl iodide → Bistrimethylsilyl-3-cyanopropylphosphonate

HRID 1155181노트

반응식

HRID 1155181 반응식
C([O:3][P:4]([CH2:9][CH2:10][CH2:11][C:12]#[N:13])(=[O:8])[O:5]CC)C.[CH3:14][Si:15](I)([CH3:17])[CH3:16]>C(Cl)(Cl)(Cl)Cl>[CH3:14][Si:15]([O:3][P:4]([CH2:9][CH2:10][CH2:11][C:12]#[N:13])(=[O:8])[O:5][Si:15]([CH3:17])([CH3:16])[CH3:14])([CH3:17])[CH3:16]

참가 물질

4

반응물 2

HCID 85247Trimethylsilyl iodideHCID 2526874-Diethoxyphosphorylbutanenitrile

생성물 1

HCID 20562954Bistrimethylsilyl-3-cyanopropylphosphonate

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

반응 조건

온도
0 °C

실험 절차

In an experiment to demonstrate this method, 4.0 g of diethyl-3-cyanopropylphosphonate in 12 ml of carbon tetrachloride, was treated with 5.6 ml of trimethylsilyl iodide. This was cooled to 0° C. and stirred for ten minutes, and allowed to warm to room temperature, forming bis(trimethylsilyl)-3-cyanopropylphosphonate.

후처리

  1. temperatureto warm to room temperature

출처 및 근거

ORD 기록
ord-730bd60a21a148278b07a80ebc00947c
출처 데이터셋
uspto-grants-1981_11
특허 번호
US04299943

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