Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropylamine → N-[3-(4-methylpiperazin-1-yl)propyl]-4-nitro-1-aminobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropylamine | HCID 7912 | — |
| 반응물 | p-Fluoronitrobenzene | HCID 9590 | — |
| 반응물 | 1-(3-Aminopropyl)-4-methylpiperazine | HCID 78328 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | N-[3-(4-methylpiperazin-1-yl)propyl]-4-nitro-1-aminobenzene | HCID 21975010 | — |
반응 단계
A mixture of 4.44 mL of p-fluoronitrobenzene, 6 gms. 3-(4-methyl-piperazin-1-yl)-propylamine and 6.65 mL N,N-diisopropylamine in 19 mL dioxane is heated at 105° C. for 2 days. The reaction mixture is cooled to room temperature, evaporated to dryness, and recrystallized from hot isopropanol yielding [3-(4-methyl-piperazin-1-yl)-propyl]-(4-nitro-phenyl)-amine in the amount of 0.1385 gms.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098236B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-bd5c83c4a79a42c4a343217e1748191c |
| 출처 메모 | uspto-grants-2006_08 |