Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → HCID 54354659, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 1-(Bromomethyl)-2,4-dimethylbenzene | HCID 2734604 | — |
| 반응물 | Magnesium | HCID 5462224 | — |
| 반응물 | Pimelic acid ethyl ester chloride | HCID 86738417 | — |
| 촉매 | Cadmium chloride, dihydrate | HCID 24633 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | HCID 54354659 | HCID 54354659 | 88% |
반응 단계
14.5 g of 2,4-dimethylbenzyl bromide, magnesium and cadmium chloride are used to prepare the corresponding cadmium-dialkyl by Huisgen's method. This compound is then reacted, in benzene solution at the boil, with 11.2 g of pimelic acid ethyl ester chloride. Sulphuric acid is added to the mixture, the organic phase is washed and the benzene is evaporated off. The residue is distilled in a high vacuum, giving 12.8 g of 8-(2,4-dimethylphenyl)-7-oxo-octanoic acid ethyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04334089 |
| 출처 데이터셋 | uspto-grants-1982_06 |
| ORD ID | ord-b358fc7fd22840f6a258f84de564c635 |
| 출처 메모 | uspto-grants-1982_06 |