Triethylamine → p-BROMOPHENYL 1-(p-CHLOROPHENYLSULFONYL)VINYL SULFIDE

HRID 1156385노트

반응식

HRID 1156385 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH:9]([S:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)(=[O:14])=[O:13])[CH2:10]Cl)=[CH:4][CH:3]=1.C(N(CC)CC)C>O1CCCC1.C(OCC)C>[Cl:21][C:18]1[CH:17]=[CH:16][C:15]([S:12]([C:9]([S:8][C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=2)=[CH2:10])(=[O:14])=[O:13])=[CH:20][CH:19]=1

참가 물질

5

반응물 2

HCID 8471TriethylamineHCID 130448002-CHLORO-1-(p-CHLOROPHENYLSULFONYL)ETHYL p-BROMOPHENYL SULFIDE

생성물 1

HCID 13044811p-BROMOPHENYL 1-(p-CHLOROPHENYLSULFONYL)VINYL SULFIDE수율 40.7%

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 8028Tetrahydrofuran용매

실험 절차

Thirty-five grams (82 mmoles) of 2-chloro-1-(p-chlorophenylsulfonyl)ethyl p-bromophenyl sulfide was dissolved in 100 ml of tetrahydrofuran and treated with 12 ml (86 mmoles) of triethylamine. The mixture was diluted with 100 ml of diethyl ether and allowed to stand for 15 minutes. The precipitated triethylamine hydrochloride was separated by filtration. Evaporation of solvent from the filtrate gave 35 g of crude solid m.p. 45°-95°. Recrystallization from 100 ml of ethyl acetate-pentane (45:55) gave 13 g of pure product, m.p. 97°-99°.

후처리

  1. customThe precipitated triethylamine hydrochloride was separated by filtration
  2. customEvaporation of solvent from the filtrate
  3. customgave 35 g of crude solid m.p. 45°-95°
  4. customRecrystallization from 100 ml of ethyl acetate-pentane (45:55)

출처 및 근거

ORD 기록
ord-eb4557c5d75a4e4ab7e7818c24cc9fc8
출처 데이터셋
uspto-grants-1982_06
특허 번호
US04335142

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