Dichloromethane → 5-Bromo-3-[1-(2-chloro-3-fluoro-6-hydroxyphenyl)ethyl]pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[cH:9][c:10]2[CH:11]([CH3:12])[c:13]1[c:14]([Cl:28])[c:15]([F:27])[cH:16][cH:17][c:18]1[O:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26].[CH2:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1.[Cl:42][CH2:43][Cl:44]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[cH:9][c:10]2[CH:11]([CH3:12])[c:13]1[c:14]([Cl:28])[c:15]([F:27])[cH:16][cH:17][c:18]1[OH:19]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 8082Piperidine

HCID 178437285HCID 178437285, 화합물

생성물 1

HCID 670048995-Bromo-3-[1-(2-chloro-3-fluoro-6-hydroxyphenyl)ethyl]pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-379b6637af60469bacb6a9ef5ec1e576
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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