Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1156717생성일: 2026년 10월 26일
Trichloroacetyl chloride → 5-(N-Methyl-Trichloroacetamido)-3-Trichloromethyl-1,2,4-Thiadiazole
https://huagongshe.com/reaction/1156717
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Trichloroacetyl chloride | HCID 6420 | — |
| 반응물 | N-Methyl-3-(trichloromethyl)-1,2,4-thiadiazol-5-amine | HCID 13150493 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 5-(N-Methyl-Trichloroacetamido)-3-Trichloromethyl-1,2,4-Thiadiazole | HCID 12851602 | 92% |
반응 단계
A solution of 5.8 grams (0.02 mole) 5-methylamino-3-trichloromethyl-1,2,4-thiadiazole and 9.0 grams (0.05 mole) trichloroacetyl chloride in 200 milliliters toluene was refluxed at about 110° C. for 20 hours. Upon cooling to -10° C., 2.7 grams pure product precipitated; m.p. 223° C. An additional 6.0 grams product was isolated by removal of the low boiling materials in vacuo. Total yield was 92%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04337081 |
|---|
| 출처 데이터셋 | uspto-grants-1982_06 |
|---|
| ORD ID | ord-36de979bf96c461c9ee5e39d26fdcd9c |
|---|
| 출처 메모 | uspto-grants-1982_06 |
|---|
