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HCID 13385546, 화합물 → 4,5-dihydro-2,4-dimethyl-6-(4-pyridinyl)-3(2H)-pyridazinone

HRID 1156751
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HRID 1156751 반응식
C([C:3]([N:17]1CCOCC1)([C:11]1[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=1)[CH2:4][CH:5]([CH3:10])[C:6]([O:8]C)=O)#N.CC(CC(=O)C1C=C[N:34]=[CH:33]C=1)C(OC)=O>>[CH3:33][N:34]1[C:6](=[O:8])[CH:5]([CH3:10])[CH2:4][C:3]([C:11]2[CH:12]=[CH:13][N:14]=[CH:15][CH:16]=2)=[N:17]1
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3

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HCID 13385546HCID 13385546, 화합물HCID 20533844Methyl 2-methyl-4-oxo-4-(4-pyridinyl)butanoate

생성물 1

HCID 128512414,5-dihydro-2,4-dimethyl-6-(4-pyridinyl)-3(2H)-pyridazinone

실험 절차

Following the procedure described in Example A-16 but using in place of methyl 4-cyano-4-(4-morpholinyl)-4-(4-pyridinyl)-2-methylbutanoate a molar equivalent quantity of methyl 2-methyl-4-oxo-4-(4-pyridinyl)butanoate, it is contemplated that there can be obtained 4,5-dihydro-2,4-dimethyl-6-(4-pyridinyl)-3(2H)-pyridazinone. Also, this same compound can be obtained following the procedure described in Example A-1 but using in place of 4-oxo-4-(4-pyridinyl)butanenitrile a molar equivalent quantity of 2-methyl-4-oxo-4-(4-pyridinyl)butanenitrile.

출처 및 근거

ORD 기록
ord-d2258d38ba5742f7be5662b083bc231e
출처 데이터셋
uspto-grants-1982_06
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04337253

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