4-Fluorobenzoyl chloride → 1-(4-Fluorobenzoylamino)-2-(2-methylphenyl)ethane

반응식

[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:10].[F:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](Cl)=[O:17])=[CH:14][CH:13]=1>>[F:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([NH:1][CH2:2][CH2:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[CH3:10])=[O:17])=[CH:14][CH:13]=1

참가 물질

반응물 2

HCID 678794-Fluorobenzoyl chloride

HCID 20638682-Methylphenethylamine

생성물 1

HCID 128518101-(4-Fluorobenzoylamino)-2-(2-methylphenyl)ethane

실험 절차

1-Amino-2-(2-methylphenyl)ethane was reacted with 4-fluorobenzoyl chloride in the same way as in step (a) of Example 1 to afford 1-(4-fluorobenzoylamino)-2-(2-methylphenyl)ethane as colorless needles having a melting point of 82° to 83° C.

출처 및 근거

ORD 기록: ord-664993288dc9440389d86bd15832ef3f
출처 데이터셋: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04337256

반응 노트

불러오는 중…