Chlorosuccinimide → HCID 12851836, 화합물

반응식

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[C:13]([CH3:18])[CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1.[Cl:19]N1C(=O)CCC1=O>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[C:13]([CH2:18][Cl:19])[CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 31398Chlorosuccinimide

HCID 128518351-(4-Fluorophenyl)-5-methylisoquinoline

생성물 1

HCID 12851836HCID 12851836, 화합물

실험 절차

1-(4-Fluorophenyl)-5-methylisoquinoline was reacted with N-chlorosuccinimide in the same way as in step (a) of Example 2 to afford 1-(4-flurophenyl)-5-chloromethylisoquinoline as colorless needles having a melting point of 109.5° to 111.5° C.

출처 및 근거

ORD 기록: ord-a359f9b13b77468893868f6196cf1a24
출처 데이터셋: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04337256

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