1-(4-Methylphenyl)isoquinoline-5-acetonitrile → HCID 20533917, 화합물

HRID 1156934노트

반응식

HRID 1156934 반응식
C1(C2C3C(=C(CO)C=CC=3)C=CN=2)C=CC=CC=1.C[C:20]1[CH:25]=[CH:24][C:23]([C:26]2[C:35]3[CH:34]=[CH:33][CH:32]=[C:31]([CH2:36][C:37]#[N:38])[C:30]=3[CH:29]=[CH:28][N:27]=2)=[CH:22][CH:21]=1>>[CH2:23]([C:26]1[C:35]2[CH:34]=[CH:33][CH:32]=[C:31]([CH2:36][C:37]#[N:38])[C:30]=2[CH:29]=[CH:28][N:27]=1)[CH2:22][CH2:21][CH2:20][CH2:25][CH3:24]

참가 물질

3

반응물 2

HCID 128518461-(4-Methylphenyl)isoquinoline-5-acetonitrileHCID 12851849HCID 12851849, 화합물

생성물 1

HCID 20533917HCID 20533917, 화합물

실험 절차

1-Amino-2-(2-chlorophenyl)ethane and n-heptanoyl chloride were reacted in the same way as in step (a) of Example 13 to afford 1-n-heptanoylamino-2-(2-chlorophenyl)ethane as an oil. The product was successively reacted in the same way as in steps (b), (c), (d), (e), (f), (g) and (h) of Example 13 to afford 1-n-hexylisoquinoline-5-acetonitrile.

출처 및 근거

ORD 기록
ord-80e28791443c44b49567ff62c1d38766
출처 데이터셋
uspto-grants-1982_06
특허 번호
US04337256

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