Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (R)-3-amino-1-carbomethoxymethyl-3,4-dihydrocarbostyril hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | (R)-3-t-butyloxycarbonylamino-1-carbomethoxymethyl-3,4-dihydrocarbostyril | HCID 69194872 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | (R)-3-amino-1-carbomethoxymethyl-3,4-dihydrocarbostyril hydrochloride | HCID 69197166 | — |
반응 단계
(R)-3-t-butyloxycarbonylamino-1-carbomethoxymethyl-3,4-dihydrocarbostyril (20 mg) was dissolved in 4 M hydrogen chloride in 1,4-dioxane solution (5 mL) at room temperature. After 1 h the solvent was evaporated under vacuum, and the residue was twice taken up in toluene (10 mL) and evaporated under vacuum to provide (R)-3-amino-1-carbomethoxymethyl-3,4-dihydrocarbostyril hydrochloride, a white solid (21 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098235B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-78cfe89bac18470c801689497e4e731f |
| 출처 메모 | uspto-grants-2006_08 |