Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Methanesulfonic acid 2-(5-bromo-benzothiazol-2-yl)-ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Methanesulfonyl chloride | HCID 31297 | — |
| 반응물 | 5-Bromo-2-benzothiazoleethanol | HCID 21980060 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Methanesulfonic acid 2-(5-bromo-benzothiazol-2-yl)-ethyl ester | HCID 21041502 | — |
반응 단계
To a mixture of 2-(5-bromo-benzothiazol-2-yl)-ethanol (0.94 g, 3.6 mmol) in 10 mL CH2Cl2, Et3N (0.99 g, 9.8 mmol), was added methanesulfonyl chloride (0.46 g, 4.0 mmol) dropwise at room temperature. The reaction was worked up by concentrating under vacuum and then used in the next step, Example 1C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07807697B2 |
| 출처 데이터셋 | uspto-grants-2010_10 |
| ORD ID | ord-2746bde129f349149ae3c7d803d51c29 |
| 출처 메모 | uspto-grants-2010_10 |