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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1158758생성일: 2026년 10월 26일

9-ethyl-2-(methylamino)-9H-pyrido[2,3-b]indole-3-carboxamide → tert-butyl{(1S)-2-[3-(aminocarbonyl)-2-(methylamino)-9H-pyrido[2,3-b]indol-9-yl]-1-methylethyl}carbamate

https://huagongshe.com/reaction/1158758

반응식

참여 물질

역할이름HCID투입량
반응물9-ethyl-2-(methylamino)-9H-pyrido[2,3-b]indole-3-carboxamideHCID 24900932—
반응물tert-butyl {(1S)-2-[2-amino-3-(aminocarbonyl)-9h-pyrido[2,3-b]indol-9-yl]-1-methylethyl}carbamateHCID 59513639—
생성물tert-butyl{(1S)-2-[3-(aminocarbonyl)-2-(methylamino)-9H-pyrido[2,3-b]indol-9-yl]-1-methylethyl}carbamateHCID 5951364589%

반응 단계

tert-butyl{(1S)-2-[2-amino-3-(aminocarbonyl)-9H-pyrido[2,3-b]indol-9-yl]-1-methylethyl}carbamate (xvi-b, 20 mg, 0.052 mmol) was alkylated according to procedure detailed in the preparation of 48, to afford tert-butyl{(1S)-2-[3-(aminocarbonyl)-2-(methylamino)-9H-pyrido[2,3-b]indol-9-yl]-1-methylethyl}carbamate (xxxii-a, 20 mg, 89%). NH4OAc QC conditions. M+H=398.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07812018B2
출처 데이터셋uspto-grants-2010_10
ORD IDord-02f9b21527d4454f9db4f3dcf002d877
출처 메모uspto-grants-2010_10