(4E)-N-Methoxy-6-methyl-3,4-dihydro-2H-1-benzopyran-4-imine → 6-Chloro-7-methyl-3,4-dihydro-2H-1-benzopyran-4-amine

HRID 1158800노트

반응식

HRID 1158800 반응식
CO[N:3]=[C:4]1[C:13]2[C:8](=[CH:9][C:10]([CH3:15])=[C:11]([Cl:14])[CH:12]=2)[O:7][CH2:6][CH2:5]1.CON=C1C2C(=CC=C(C)C=2)OCC1>>[Cl:14][C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][C:10]=1[CH3:15])[O:7][CH2:6][CH2:5][CH:4]2[NH2:3]

참가 물질

3

반응물 2

HCID 86605441(4E)-N-Methoxy-6-methyl-3,4-dihydro-2H-1-benzopyran-4-imineHCID 866054426-Chloro-7-methylchroman-4-one O-methyl oxime

생성물 1

HCID 166430296-Chloro-7-methyl-3,4-dihydro-2H-1-benzopyran-4-amine

실험 절차

The title compound was prepared using the procedure as described in Example 7B, substituting the product of Example 13A for the product of Example 7A. 1H NMR (300 MHz, CDCl3) δ 7.27 (s, 1H), 6.68 (s, 1H), 4.15-4.29 (m, 2H), 3.98 (m, 1H), 2.29 (s, 3H), 2.07-2.17 (m, 1H), 1.75-1.85 (m, 1H). MS (DCI) m/e 198(M+H)+.

출처 및 근거

ORD 기록
ord-d659bab87a5143e2875e575db3d612df
출처 데이터셋
uspto-grants-2010_10
특허 번호
US07812019B2

반응 노트

불러오는 중…