Ammonia → 3,4-Dihydro-2H-1-benzopyran-4-amine

HRID 1158802노트

반응식

HRID 1158802 반응식
CO[N:3]=[C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[O:7][CH2:6][CH2:5]1.CON=C1C2C(=CC=C(C)C=2)OCC1.N>>[O:7]1[C:8]2[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:4]([NH2:3])[CH2:5][CH2:6]1

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 54035320Chroman-4-one O-methyl-oximeHCID 86605441(4E)-N-Methoxy-6-methyl-3,4-dihydro-2H-1-benzopyran-4-imine

생성물 1

HCID 49619573,4-Dihydro-2H-1-benzopyran-4-amine

실험 절차

The title compound was prepared using the procedure as described in Example 7B, substituting the product of Example 16A for the product of Example 7A. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.32 (dd, J 1.0 and 7.5 Hz, 1H), 7. 05 (m, 1H), 6.81 (m, 1H), 6.70 (dd, J 1.0 and 7.5 Hz, 1H), 4.27-4.08 (m, 2H), 3.83 (t, J 6.0 Hz, 1H), 2.03-1.66 (m, 4H). MS (DCI/NH3) m/e 150 (M+H)+.

출처 및 근거

ORD 기록
ord-36455fce63114ce58a8e230d7d86b904
출처 데이터셋
uspto-grants-2010_10
특허 번호
US07812019B2

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