Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-[tert-butoxycarbonyl]-L-serine → (R)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-[tert-butoxycarbonyl]-L-serine | HCID 98766 | — |
| 반응물 | (R)-2-tert-butoxycarbonylamino-3-hydroxy propionic acid | HCID 637603 | — |
| 반응물 | (S)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride | HCID 18599716 | — |
| 생성물 | (R)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride | HCID 69195062 | — |
반응 단계
(R)-3-amino-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride salt was prepared from N-t-butyloxycarbonyl-D-serine by the procedures described in Itoh, et al., Chem. Pharm. Bull. 1986, 34, 1128–1147 for the preparation of (S)-3-amino-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride salt from N-t-butyloxycarbonyl-L-serine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098235B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-7c264e9779284e15bdd86025c4faf7dd |
| 출처 메모 | uspto-grants-2006_08 |