참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phosphorus tribromide | HCID 24614 | — |
| 반응물 | 2,4-Dimethylbenzyl alcohol | HCID 27809 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-(Bromomethyl)-2,4-dimethylbenzene | HCID 2734604 | — |
반응 단계
5 g of (2,4-dimethylphenyl)methanol are dissolved in 100 ml of ether. The reaction mixture is cooled to 0° C. It is admixed dropwise with 5.2 ml of phosphorus tribromide. It is stirred at ambient temperature overnight. The reaction mixture is poured onto ice and extracted with AcOEt. The organic phase is washed with saturated NaCl solution. The organic phase is dried over MgSO4, filtered and evaporated to dryness. This gives 7.3 g of the expected compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07812165B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_10 |
|---|
| ORD ID | ord-d73d118dd0614b2d8413423dd397717a |
|---|
| 출처 메모 | uspto-grants-2010_10 |
|---|
