O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine → 1-Amino-4-[(phenylmethyl)oxy]pyridinium 2,4,6-trimethylbenzenesulfonate

HRID 1159944노트

반응식

HRID 1159944 반응식
[NH2:1][O:2][S:3]([C:6]1[C:11]([CH3:12])=[CH:10][C:9]([CH3:13])=[CH:8][C:7]=1[CH3:14])(=[O:5])=[O:4].[C:15]1([CH2:21][O:22][C:23]2[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(Cl)Cl>[CH3:12][C:11]1[CH:10]=[C:9]([CH3:13])[CH:8]=[C:7]([CH3:14])[C:6]=1[S:3]([O-:5])(=[O:4])=[O:2].[NH2:1][N+:26]1[CH:27]=[CH:28][C:23]([O:22][CH2:21][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:24][CH:25]=1

참가 물질

4

반응물 2

HCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamineHCID 123288284-(Benzyloxy)pyridine

생성물 1

HCID 866187801-Amino-4-[(phenylmethyl)oxy]pyridinium 2,4,6-trimethylbenzenesulfonate

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

A solution of 2-[(aminooxy)sulfonyl]-1,3,5-trimethylbenzene (4.05 g, 18.8 mmol) in DCM (60 mL) was cooled to 0° C. 4-[(Phenylmethyl)oxy]pyridine (2.91 g, 15.7 mmol) in DCM (2 mL) was added dropwise. Following complete addition, the mixture was stirred at rt for 45 min. The reaction mixture was evaporated under reduced pressure to give crude white foam.

후처리

  1. additionaddition
  2. customThe reaction mixture was evaporated under reduced pressure
  3. customto give crude white foam

출처 및 근거

ORD 기록
ord-cef7e192d3b84e339fce7f47090bd9f6
출처 데이터셋
uspto-grants-2010_10
특허 번호
US07812022B2

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