Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl bromoacetate → 2-Trifluromethyl-4-nitrophenoxyacetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl bromoacetate | HCID 7748 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Phenol, 4-nitro-2-(trifluoromethyl)- | HCID 3014014 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | 2-Trifluromethyl-4-nitrophenoxyacetic acid ethyl ester | HCID 19261608 | 95% |
반응 단계
A mixture of 2-trifluoromethyl-4-nitrophenol (73.4 g, 0.354 mol), ethyl bromoacetate (65.2 g, 0.39 mol), potassium carbonate (58.7 g, 0.425 mol) and 2-butanone (400 mL) was refluxed under stirring for 10 h. The solid was filtered off, the filtrate was evaporated and the residue was fractionated yielding 97.8 g (95%) of 2-trifluromethyl-4-nitrophenoxyacetic acid ethyl ester, b.p. 126° C./40 Pa.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07816385B2 |
| 출처 데이터셋 | uspto-grants-2010_10 |
| ORD ID | ord-79e7ca7fc78b4de0abd00959d8e0b2bc |
| 출처 메모 | uspto-grants-2010_10 |