Cyclohexanethiol → Methyl 4-[4-(cyclohexylcarbamoyl)-5-cyclohexylsulfanylpyrazol-1-yl]benzoate
반응식
[CH2:1]1[CH2:6][CH2:5][CH:4]([SH:7])[CH2:3][CH2:2]1.Cl[C:9]1[N:13]([C:14]2[CH:23]=[CH:22][C:17]([C:18]([O:20][CH3:21])=[O:19])=[CH:16][CH:15]=2)[N:12]=[CH:11][C:10]=1[C:24](=[O:32])[NH:25][CH:26]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1>>[CH:26]1([NH:25][C:24]([C:10]2[CH:11]=[N:12][N:13]([C:14]3[CH:15]=[CH:16][C:17]([C:18]([O:20][CH3:21])=[O:19])=[CH:22][CH:23]=3)[C:9]=2[S:7][CH:4]2[CH2:5][CH2:6][CH2:1][CH2:2][CH2:3]2)=[O:32])[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1참가 물질
3
실험 절차
Methyl 4-[4-(cyclohexylcarbamoyl)-5-cyclohexylsulfanylpyrazol-1-yl]benzoate was prepared from cyclohexylthiol and methyl 4-[5-chloro-4-(cyclohexylcarbamoyl)pyrazol-1-yl]benzoate (Intermediate#15) by the same process used for Intermdiate#96.
출처 및 근거
- ORD 기록
- ord-e8cd59eb7e184244a9219974985cba16
- 출처 데이터셋
- uspto-grants-2010_10