2-Amino-5-iodopyrimidine → 5-[6-(4-Chloro-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-ylethynyl]-pyrimidin-2-ylamine

반응식

[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH3:19])[c:11]3[n:12]([cH:13]2)[c:14]([C:17]#[CH:18])[cH:15][n:16]3)[cH:6][cH:7]1.[NH2:20][c:21]1[n:22][cH:23][c:24]([I:27])[cH:25][n:26]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH3:19])[c:11]3[n:12]([cH:13]2)[c:14]([C:17]#[C:18][c:24]2[cH:23][n:22][c:21]([NH2:20])[n:26][cH:25]2)[cH:15][n:16]3)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 2411022-Amino-5-iodopyrimidine

HCID 866080946-(4-Chloro-phenyl)-3-ethynyl-8-methyl-imidazo[1,2-a]pyridine

생성물 1

HCID 167384795-[6-(4-Chloro-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-ylethynyl]-pyrimidin-2-ylamine

출처 및 근거

ORD 기록: ord-6585e8d5d3e44237b2e4d1ecdd863eb2
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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