Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4,6-Tri-t-butyl-1-bromobenzene → Racemic 3-{4-[1-(2,4,6-tri-t-butyl-phenoxy)-5,5,5-trifluoro-pentyl]-benzoylamino}-propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4,6-Tri-t-butyl-1-bromobenzene | HCID 138089 | — |
| 반응물 | 3-(4-{5,5,5-Trifluoro-1-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-phenoxy]-pentyl}-benzoylamino)-propionic acid methyl ester | HCID 67153418 | — |
| 생성물 | Racemic 3-{4-[1-(2,4,6-tri-t-butyl-phenoxy)-5,5,5-trifluoro-pentyl]-benzoylamino}-propionic acid | HCID 67153428 | — |
반응 단계
The title compound is prepared in a manner substantially similar to Example 359 starting from 3-(4-{5,5,5-trifluoro-1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pentyl}-benzoylamino)-propionic acid methyl ester and 2-bromo-1,3,5-tri-tert-butyl-benzene. MS: 652.2 [M−H]−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07816557B2 |
| 출처 데이터셋 | uspto-grants-2010_10 |
| ORD ID | ord-8d5ca36a0fbf4ccfa8ab418af2b507fb |
| 출처 메모 | uspto-grants-2010_10 |