Benzoic acid, 2-hydrazinyl-, hydrochloride (1:1) → (S)-2-(3-{(4-carbamimidoylphenylamino)-[2-fluoro-4-(2-hydroxyethoxy)-5-methoxyphenyl]methyl}-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl)benzoic acid

반응식

CO[C:3](=[O:42])[N:4]=[C:5](SC)[C:6]([C:20]1[CH:25]=[C:24]([O:26][CH3:27])[C:23]([O:28][CH2:29][CH2:30][O:31][Si](C(C)(C)C)(C)C)=[CH:22][C:21]=1[F:39])=[N:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[N:18]=C(C)O[N:15]=2)=[CH:10][CH:9]=1.Cl.[NH:44]([C:46]1[CH:54]=[CH:53][CH:52]=[CH:51][C:47]=1[C:48]([OH:50])=[O:49])[NH2:45].COC(=O)N=C(SC)C(C1C=C(OC)C=C(OCCF)C=1F)=NC1C=CC(C2N=C(C)ON=2)=CC=1.N(C1N=CC=CN=1)N>>[C:14]([C:11]1[CH:10]=[CH:9][C:8]([NH:7][C@@H:6]([C:20]2[CH:25]=[C:24]([O:26][CH3:27])[C:23]([O:28][CH2:29][CH2:30][OH:31])=[CH:22][C:21]=2[F:39])[C:5]2[NH:4][C:3](=[O:42])[N:44]([C:46]3[CH:54]=[CH:53][CH:52]=[CH:51][C:47]=3[C:48]([OH:50])=[O:49])[N:45]=2)=[CH:13][CH:12]=1)(=[NH:18])[NH2:15]