(2R)-1-Ethyl-2-pyrrolidinemethanamine → {[(2R)-1-Ethylpyrrolidin-2-yl]methyl}(5-nitro-1-benzofuran-7-yl)amine
반응식
[N:1]1([CH2:7][CH2:8][NH:9][C:10]2[C:18]3[O:17][CH:16]=[CH:15][C:14]=3[CH:13]=[C:12]([N+:19]([O-:21])=[O:20])[CH:11]=2)[CH2:6][CH2:5]O[CH2:3][CH2:2]1.N[CH2:23][C@H]1CCCN1CC>>[CH2:2]([N:1]1[CH2:6][CH2:5][CH2:23][C@@H:7]1[CH2:8][NH:9][C:10]1[C:18]2[O:17][CH:16]=[CH:15][C:14]=2[CH:13]=[C:12]([N+:19]([O-:21])=[O:20])[CH:11]=1)[CH3:3]참가 물질
3
실험 절차
The title compound was prepared according to the procedure described for Intermediate 27 using (R)-2-aminomethyl-1-ethylpyrrolidine. Yield: 100%, HPLC purity=90%, m/z=290 (M+H)+.
출처 및 근거
- ORD 기록
- ord-f564c1ba413f4563bf0593b460b026f0
- 출처 데이터셋
- uspto-grants-2010_10
- 특허 번호
- US07820675B2
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