5-Methylnicotinic acid → N-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-5-methylnicotin-amide

반응식

[CH3:21][c:22]1[cH:23][c:24]([C:28](=[O:29])[OH:30])[cH:25][n:26][cH:27]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH2:20])[cH:11][n:12][c:13]2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH:20][C:28]([c:24]3[cH:23][c:22]([CH3:21])[cH:27][n:26][cH:25]3)=[O:29])[cH:11][n:12][c:13]2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:6][cH:7]1

참가 물질

반응물 2

HCID 2562085-Methylnicotinic acid

HCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

생성물 1

HCID 56961334N-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-5-methylnicotin-amide

출처 및 근거

ORD 기록: ord-4780965f16034b1ca7e9fefaba3ab7d2
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…