Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → HCID 178502891, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| 반응물 | 3-Chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid | HCID 2821908 | — |
| 반응물 | 3-Chloro-5-trifluoromethyl-pyridine-2-carbonyl chloride | HCID 22013555 | — |
| 생성물 | HCID 178502891 | HCID 178502891 | — |
반응 단계
For example, 3-chloro-5-trifluoromethylpyridine-2-carboxylic acid is reacted with thionyl chloride whereby 3-chloro-5-trifluoromethylpicolinoyl chloride can be obtained. This compound is reacted with O-methylhydroxyamine hydrochloride at room temperature for 4 hours in the presence of potassium carbonate to obtain N-methoxy-3-chloro-5-trifluoromethylpyridine-2-carboximidic acid which is then reacted with O,O-diethylthionophospholic acid diester chloride at 50° C. for 24 hours in the presence of potassium carbonate to thereby obtain O,O-diethyl-O-(N-methoxy-3-chloro-5-trifluoromethylpyridine-2-carboximidoyl)thionophosphate (nD16.0 = 1.5054).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04367336 |
| 출처 데이터셋 | uspto-grants-1983_01 |
| ORD ID | ord-4bb67fd5170049c6971c9cc801db676f |
| 출처 메모 | uspto-grants-1983_01 |