Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → Aniracetam
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | p-Anisoyl chloride | HCID 7477 | — |
| 반응물 | 2-Pyrrolidone | HCID 12025 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Aniracetam | HCID 2196 | — |
반응 단계
20 g. of p-methoxybenzoyl chloride and 20 g. of 2-pyrrolidinone are boiled at reflux in 20 ml. of diethyl ether for 16 hours and then diethyl ether, ice and 2-N aqueous ammonia are added to the mixture. The insoluble constituents are filtered off and washed ion-free with diethyl ether and water. The filter cake is dried and there is obtained 1-(p-methoxybenzoyl)-2-pyrrolidinone having a melting point of 119.5°-120.5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04369139 |
| 출처 데이터셋 | uspto-grants-1983_01 |
| ORD ID | ord-0bb0b4da28074479be7395265e460878 |
| 출처 메모 | uspto-grants-1983_01 |