HCID 53792849, 화합물 → HCID 54044274, 화합물

HRID 1164369노트

반응식

HRID 1164369 반응식
C([N:3]([CH:13]([CH3:15])[CH3:14])[C:4]([C:6]1[NH:7][C:8]([Cl:12])=[C:9]([Cl:11])[N:10]=1)=[O:5])=O>S(=O)(=O)(O)O>[CH:13]([NH:3][C:4]([C:6]1[NH:7][C:8]([Cl:12])=[C:9]([Cl:11])[N:10]=1)=[O:5])([CH3:15])[CH3:14]

참가 물질

3

반응물 1

HCID 53792849HCID 53792849, 화합물

생성물 1

HCID 54044274HCID 54044274, 화합물수율 72%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

25 g (0.1 mol) of 4,5-dichloro-imidazole-2-carboxylic acid N-formyl-isopropylamide were stirred with 200 ml of concentrated sulphuric acid for about 15 minutes at 50°-70° C. After cooling, the mixture was poured onto ice and the product was filtered off, washed with water until neutral and dried. In this way, 16 g (72% of theory) of 4,5-dichloro-imidazole-2-carboxylic acid isopropylamide with a melting point of 150° C. were obtained.

후처리

  1. temperatureAfter cooling
  2. additionthe mixture was poured onto ice
  3. filtrationthe product was filtered off
  4. washwashed with water until neutral and
  5. customdried

출처 및 근거

ORD 기록
ord-a90fb5a04fa941f188f83da3da3ef0c7
출처 데이터셋
uspto-grants-1983_01
특허 번호
US04369186

반응 노트

불러오는 중…