Thionyl Chloride → 2-[(Phenylmethyl)thio]benzoyl chloride

HRID 1164723

반응식

HRID 1164723 반응식
[C:1]1([CH2:7][S:8][C:9]2[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=2[C:11](O)=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:20])=O>C1C=CC=CC=1>[C:1]1([CH2:7][S:8][C:9]2[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=2[C:11]([Cl:20])=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 2641822-(Benzylsulfanyl)benzoic acid

생성물 1

HCID 200673402-[(Phenylmethyl)thio]benzoyl chloride수율 94.1%

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

A suspension of 100 g of 2-[(phenylmethyl)thio]benzoic acid and 97.6 g of thionyl chloride in 800 ml of benzene was refluxed for about three hours then evaporated to dryness under vacuum. The residue was triturated with hexane to yield 101.2 g of 2-[(phenylmethyl)thio]benzoyl chloride, m.p. 113° to 116° C.

후처리

  1. temperaturewas refluxed for about three hours
  2. customthen evaporated to dryness under vacuum
  3. customThe residue was triturated with hexane

출처 및 근거

ORD 기록
ord-6fc63a9e303d43e2bf6ca3d5569fc421
출처 데이터셋
uspto-grants-1990_03
특허 번호
US04906282

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