Potassium Carbonate → 2-Phenylpropionic acid
반응식
Cl[CH:2](C)[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=O.[C:12](=O)([O-:14])[O-:13].[K+].[K+].[Hg:18]>CO>[C:5]1([CH:3]([CH3:2])[C:12]([OH:14])=[O:13])[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1.[Hg:18]참가 물질
6
실험 절차
A solution comprising 5 parts of α-chloropropiophenone and 3 parts of anyhydrous potassium carbonate in 300 parts of anhydrous methyl alcohol was irradiated by means of a medium pressure 200W mercury vapour lamp for 6 hours at 30° C. The solvent was removed by distillation and the resulting methyl ester of α-phenyl propionic acid was treated with 10% w/v aqueous alcoholic sodium hydroxide at 100° C. for 3 hours to effect hydrolysis and thereby to yield 3.2 parts of α-phenyl propionic acid b.p. 125° C. at 20 mm mercury.
후처리
- customThe solvent was removed by distillation
- additionthe resulting methyl ester of α-phenyl propionic acid was treated with 10% w/v aqueous alcoholic sodium hydroxide at 100° C. for 3 hours
- customhydrolysis
출처 및 근거
- ORD 기록
- ord-1148093dfc9f4539bce02c20aeaf5ff4
- 출처 데이터셋
- uspto-grants-1990_03
- 특허 번호
- US04906343
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