Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Hydroxide → 4-chloro-2-(4-chlorophenyl)-5-{(6-chloro-3-pyridyl)-methyloxy}-3(2H)-pyridazinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | (6-Chloropyridin-3-yl)methanol | HCID 177161 | — |
| 반응물 | 4,5-Dichloro-2-(4-chlorophenyl)-3(2H)-pyridazinone | HCID 779402 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-chloro-2-(4-chlorophenyl)-5-{(6-chloro-3-pyridyl)-methyloxy}-3(2H)-pyridazinone | HCID 3639225 | 61.2% |
반응 단계
The procedures in Synthesis Example 2 were repeated by using 2.0 g (7.2 m mol) of 2-(4-chlorophenyl)-4,5-dichloro-3(2H)-pyridazinone, 1.1 g (7.7 m mol) of 6-chloro-3-pyridine methanol, 0.4 g of potassium hydroxide and 80 ml of N,N-dimethylformamide to give 1.7 g of the intended product (recrystallized from benzene/n-hexane).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04910201 |
| 출처 데이터셋 | uspto-grants-1990_03 |
| ORD ID | ord-6690ea97cf5545289c0658e98f2f1891 |
| 출처 메모 | uspto-grants-1990_03 |