Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aniline → Ethyl 3-anilinobut-2-enoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Ethyl 3-anilinobut-2-enoate | HCID 94928 | — |
반응 단계
Aniline (0.20 mol) and ethylacetoacetate (0.20 mol) are mixed in toluene (200 mL) containing 0.04 g of p-toluenesulfonic acid-hydrate and heated at reflux under a water separator for one hour. The toluene is removed under vacuum to afford the ethyl-3-phenylaminobut-2-enoate which can be used as is for the preparation of the ethyl 2-methyl-3-quinolinecarboxylate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04910327 |
| 출처 데이터셋 | uspto-grants-1990_03 |
| ORD ID | ord-94f9fe33b8f246e79fa026b72244ccc5 |
| 출처 메모 | uspto-grants-1990_03 |