2-Bromopyridine → 4-(4-Methylpyrimidin-2-YL)benzaldehyde

HRID 1166090노트

반응식

HRID 1166090 반응식
[CH:1]([C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1)=[O:2].Br[C:13]1[N:18]=[C:17]([CH3:19])[CH:16]=[CH:15][N:14]=1.C(C1C=C(B(O)O)C=CC=1)=O.BrC1C=CC=CN=1>>[CH3:19][C:17]1[CH:16]=[CH:15][N:14]=[C:13]([C:6]2[CH:7]=[CH:8][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=2)[N:18]=1

참가 물질

5

반응물 4

HCID 79732-BromopyridineHCID 5910734-Formylphenylboronic AcidHCID 27343563-Formylphenylboronic acidHCID 109429282-Bromo-4-methylpyrimidine

생성물 1

HCID 226308614-(4-Methylpyrimidin-2-YL)benzaldehyde

실험 절차

The title compound was prepared by a procedure analogous to Reference Example 12 by substituting 4-formylphenylboronic acid and 2-bromo-4-methylpyrimidine (prepared as described in Helv. Chim. Acta 1992, 75, 1621) for the 3-formylphenylboronic acid and 2-bromopyridine, respectively, of Reference Example 12. MS 199 (M+H)+.

출처 및 근거

ORD 기록
ord-92676adcd14743c6bb791e311fd8ce20
출처 데이터셋
uspto-grants-2003_09
특허 번호
US06613747B2

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