Ammonia → 5-Chloro-2-methoxybenzene-1-sulfonamide
반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:12][CH3:13])=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:7]=1.[NH3:14]>O1CCCC1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:12][CH3:13])=[C:6]([S:8]([NH2:14])(=[O:10])=[O:9])[CH:7]=1참가 물질
4
실험 절차
To a solution of 5-chloro-2-methoxybenzene sulfonyl chloride (1.0 g, 4.15 mmol) in tetrahydrofuran (10 mL) was bubbled ammonia gas until saturated. The reaction was stirred overnight. The white solid that precipitated out of solution was collected by filtration and washed with dichloromethane to give the title compound (0.52 g).
후처리
- customThe white solid that precipitated out of solution
- filtrationwas collected by filtration
- washwashed with dichloromethane
출처 및 근거
- ORD 기록
- ord-f40b87c7e96a4cb98fe793f02a60727f
- 출처 데이터셋
- uspto-grants-2006_08
- 특허 번호
- US07098212B2
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