Dimethylformamide → HCID 22998390, 화합물

반응식

CN(C=O)C.[S:6]([Cl:10])(Cl)(=[O:8])=[O:7].[CH:11]([C:14]1[S:18][C:17]2[CH:19]=[CH:20][CH:21]=[CH:22][C:16]=2[CH:15]=1)([CH3:13])[CH3:12]>>[CH:11]([C:14]1[S:18][C:17]2[CH:19]=[CH:20][CH:21]=[CH:22][C:16]=2[C:15]=1[S:6]([Cl:10])(=[O:8])=[O:7])([CH3:13])[CH3:12]

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 24648Sulfuryl chloride

HCID 2705232-(Propan-2-yl)-1-benzothiophene

생성물 1

HCID 22998390HCID 22998390, 화합물

실험 절차

2-i-propylbenzo[b]thiophene-3-sulfonyl chloride compound was prepared by the method of Example 40B with DMF (5.2 mmoles, 0.40 ml), using sulfuryl chloride (4.2 mmoles, 0.34 ml) and 2-i-propyl-benzo[b]thiophene (2.1 mmoles, 0.37 g). Flash chromatography (1% ethyl acetate/hexanes) provided 0.17 g (29%) of a yellow solid.

출처 및 근거

ORD 기록: ord-1b75cd1190704d049c396ee8d464bfe0
출처 데이터셋: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06613804B2

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