Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 반응물 | 2-Ethyl-5-methylbenzo[b]thiophene | HCID 595344 | — |
| 생성물 | 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride | HCID 22998437 | — |
반응 단계
2-ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride was prepared in the same manner as described in Example 40B. Reaction of DMF (6.5 mmoles, 0.50 ml), sulfurylchloride (5.5 mmoles, 0.44 ml) and 2-ethyl-5-methylbenzo[b]thiophene (3.2 mmoles, 0.57 g) yielded, after flash chromatography, using 2% ethyl acetate/hexanes, 0.58 g (66%) of an orange solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06613804B2 |
| 출처 데이터셋 | uspto-grants-2003_09 |
| ORD ID | ord-37b90b7045074b1485a4529e85cb04fa |
| 출처 메모 | uspto-grants-2003_09 |