HCID 178451855, 화합물 → 4-[3-(4-Fluorophenyl)-5-(4-piperidinylmethyl)-1h-pyrazol-4-yl]pyridine
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O.FC1C=CC(C2NN=C(C(N3CCNCC3)=O)C=2C2C=CN=CC=2)=CC=1.[F:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[NH:39][N:38]=[C:37]([CH2:40][CH:41]3[CH2:46][CH2:45][N:44](C(OC(C)(C)C)=O)[CH2:43][CH2:42]3)[C:36]=2[C:54]2[CH:59]=[CH:58][N:57]=[CH:56][CH:55]=2)=[CH:31][CH:30]=1>>[F:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[C:36]([C:54]3[CH:55]=[CH:56][N:57]=[CH:58][CH:59]=3)=[C:37]([CH2:40][CH:41]3[CH2:46][CH2:45][NH:44][CH2:43][CH2:42]3)[NH:38][N:39]=2)=[CH:31][CH:30]=1참가 물질
3
실험 절차
4-[3-(4-Fluorophenyl)-5-(4-piperidinylmethyl)-1H-pyrazol-4-yl]pyridine was prepared using the same method as described for Example A-314, step 1 by replacing 1-[[5-(4-fluorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl]carbonyl]piperazine, monohydrate with the pyrazole of step 5 of the present Example. Anal. Calc'd for C20H21N4F.2TFA.1.25H2O: C, 49.11; H, 4.38; N, 9.54; Found: C, 48.74; H, 4.02; N, 9.57. MS (MH+): 337 (base peak).
출처 및 근거
- ORD 기록
- ord-530ac056976f40368c98d2a90ae59904