Ethyl Acetate → HCID 22993710, 화합물

HRID 1167643노트

반응식

HRID 1167643 반응식
[O:1]1[CH:5]=[C:4]([C:6]([O:8][CH3:9])=[O:7])[C:3]([C:10]([O:12][CH3:13])=[O:11])=[CH:2]1.C(OCC)(=O)C.[H][H]>CO.[Rh]>[O:1]1[CH2:5][CH:4]([C:6]([O:8][CH3:9])=[O:7])[CH:3]([C:10]([O:12][CH3:13])=[O:11])[CH2:2]1

참가 물질

6

반응물 3

HCID 8857Ethyl AcetateHCID 303461Dimethyl furan-3,4-dicarboxylateHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 22993710HCID 22993710, 화합물수율 100%

시약·촉매·용매 2

HCID 23948Rhodium촉매HCID 887Methanol용매

실험 절차

Dimethyl 3,4-furandicarboxylate (5.20 g, 28.0 mmol) was combined with 5% Rhodium/C in methanol (30 mL) and ethyl acetate (10 mL) in a Parr shaker bottle. The reaction was charged to 50 psi hydrogen and was shaken for 8.5 h. The reaction was filtered over celite, concentrated in vacuo to give the dimethyl 3,4-tetrahydrofuran dicarboxylate (5.2 g, 100%) as an oil MS (M−CH3OH)+=156.

후처리

  1. filtrationThe reaction was filtered over celite
  2. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-aadcb005d49e4a66a8b059231910b2b0
출처 데이터셋
uspto-grants-2003_09
특허 번호
US06620823B2

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