Cyclopropanecarbonyl chloride → HCID 10238665, 화합물

반응식

[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13](=[O:22])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][NH2:21])=[CH:16][CH:15]=3)[S:11][C:7]=2[C:6]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[CH:5][CH:4]=1.[CH:29]1([C:32](Cl)=[O:33])[CH2:31][CH2:30]1>>[CH:29]1([C:32]([NH:21][CH2:20][C:17]2[CH:18]=[CH:19][C:14]([C:13]([NH:12][C:10]3[S:11][C:7]4[C:6]([N:23]5[CH2:28][CH2:27][O:26][CH2:25][CH2:24]5)=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[C:8]=4[N:9]=3)=[O:22])=[CH:15][CH:16]=2)=[O:33])[CH2:31][CH2:30]1

참가 물질

반응물 2

HCID 77637Cyclopropanecarbonyl chloride

HCID 11280971HCID 11280971, 화합물

생성물 1

HCID 10238665HCID 10238665, 화합물

실험 절차

Using N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-4-aminomethyl-benzamide and cyclopropanecarbonyl chloride, the title compound was prepared as light-yellow crystals (64% yield). MS: m/e=467(M+H+).

출처 및 근거

ORD 기록: ord-3a3e9f046c28469da0b61ef13ba126b8
출처 데이터셋: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06624163B2

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