5-amino-N-[(1-butyl-4-piperidinyl)methyl]-6-chloroimidazo[1,2-a]pyridine-8-carboxamide → 5-AMINO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

HRID 1168248노트

반응식

HRID 1168248 반응식
[NH2:1][C:2]1[N:7]2[CH:8]=[CH:9][N:10]=[C:6]2[C:5]([C:11]([NH:13][CH:14]2[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][CH2:22][O:23][CH3:24])[CH2:16][CH2:15]2)=[O:12])=[CH:4][C:3]=1Cl.NC1N2C=CN=C2C(C(NCC2CCN(CCCC)CC2)=O)=CC=1Cl>>[NH2:1][C:2]1[N:7]2[CH:8]=[CH:9][N:10]=[C:6]2[C:5]([C:11]([NH:13][CH:14]2[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][CH2:22][O:23][CH3:24])[CH2:16][CH2:15]2)=[O:12])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 102701115-amino-N-[(1-butyl-4-piperidinyl)methyl]-6-chloroimidazo[1,2-a]pyridine-8-carboxamideHCID 120880945-AMINO-6-CHLORO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

생성물 1

HCID 120880955-AMINO-N-[1-(3-METHOXYPROPYL)-4-PIPERIDINYL]IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

실험 절차

The title compound was prepared according to the procedure of EXAMPLE 2 using 5-amino-6-chloro-N-[1-(3-methoxypropyl)-4-piperidinyl]imidazo[1,2-a]pyridine-8-carboxamide (EXAMPLE 3), instead of 5-amino-N-[(1-butyl-4-piperidinyl)methyl]-6-chloroimidazo[1,2-a]pyridine-8-carboxamide.

출처 및 근거

ORD 기록
ord-44642d06e2f94f77bb4b065aa3cd8aa7
출처 데이터셋
uspto-grants-2003_09
특허 번호
US06624162B2

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