4-Aminomethyl-1-N-butylpiperidine → 5-Amino-n-[(1-butyl-4-piperidinyl)methyl]-6-chloro-2-phenylimidazo[1,2-a]pyridine-8-carboxamide
반응식
[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[N:10]=[C:6]2[C:5]([C:17]([OH:19])=O)=[CH:4][C:3]=1[Cl:20].[CH2:21]([N:25]1[CH2:30][CH2:29][CH:28]([CH2:31][NH2:32])[CH2:27][CH2:26]1)[CH2:22][CH2:23][CH3:24]>>[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:10]=[C:6]2[C:5]([C:17]([NH:32][CH2:31][CH:28]2[CH2:29][CH2:30][N:25]([CH2:21][CH2:22][CH2:23][CH3:24])[CH2:26][CH2:27]2)=[O:19])=[CH:4][C:3]=1[Cl:20]참가 물질
3
실험 절차
The title compounds were prepared according to the procedure described in the step 3 in EXAMPLE 5 from 5-amino-6-chloro-2-phenylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 22, Step 2) and 1-(1-butyl-4-piperidinyl)methanamine (EXAMPLE 1, METHOD A, Step 5).
출처 및 근거
- ORD 기록
- ord-6dec1792ba074462b63065a097055226
- 출처 데이터셋
- uspto-grants-2003_09