Diethyl (ethoxymethylene)malonate → HCID 12083030, 화합물

반응식

[CH3:1][C:2]1([CH3:11])[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3]1.C(O[CH:15]=[C:16]([C:22]([O:24][CH2:25][CH3:26])=[O:23])[C:17]([O:19][CH2:20][CH3:21])=[O:18])C>>[CH3:1][C:2]1([CH3:11])[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]1[CH:15]=[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[C:22]([O:24][CH2:25][CH3:26])=[O:23]

참가 물질

반응물 2

HCID 6871Diethyl (ethoxymethylene)malonate

HCID 124373022,2-dimethyl-2,3-dihydro-1H-indole

생성물 1

HCID 12083030HCID 12083030, 화합물

반응 조건

온도: 105 °C

실험 절차

A mixture of 2,2-dimethylindoline (1.47 g) and diethyl ethoxymethylenemalonate (2.0 ml) is heated to 105° C. for 17 hours to afford the title compound as a pale yellow oil. Physical characteristics: 1H NMR (CDCl3) δ7.76, 7.18, 7.12, 6.97, 6.74, 4.24, 3.16, 1.50, 1.34.

출처 및 근거

ORD 기록: ord-62ec539d348e47e59aa4cc5914ae4f11
출처 데이터셋: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06624159B2

반응 노트

불러오는 중…