3-Hydroxy-2-hydroxymethyl-6-methylpyridine → 3-Hydroxy-6-methylpyridine-2-carbaldehyde
반응식
[OH:1][CH2:2][C:3]1[C:8]([OH:9])=[CH:7][CH:6]=[C:5]([CH3:10])[N:4]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[OH:9][C:8]1[C:3]([CH:2]=[O:1])=[N:4][C:5]([CH3:10])=[CH:6][CH:7]=1참가 물질
4
실험 절차
To a solution of 2-hydroxymethyl-6-methyl-pyridin-3-ol (1.0 g, 7.19 mmol) in methylene chloride (30 mL) at ambient temperature was added manganese dioxide (12.5 g, 143 mmol). The reactions was stirred for 48 hours, then filtered through celite and concentrated to give the title compound (0.070 g).
후처리
- filtrationfiltered through celite and
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-02ad876e63fb458292e9317dfd5c8fb7
- 출처 데이터셋
- uspto-grants-2006_08
- 특허 번호
- US07098212B2
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