Pyridine → 2-Pyridyl Trifluoromethanesulfonate
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:7][C:8]([F:21])([F:20])[S:9]([O:12]S(C(F)(F)F)(=O)=O)(=[O:11])=[O:10]>C(Cl)Cl>[O:12]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)[S:9]([C:8]([F:21])([F:20])[F:7])(=[O:11])=[O:10]참가 물질
4
실험 절차
In analogy to GP 2, reaction of 4.7 g Intermediate 2.1 (13 mmol), 4.2 mL dry pyridine (53 mmol), 3.5 ml trifluoromethanesulfonic acid anhydride (21 mmol) in 150 mL DCM yielded 4.8 g 2-pyridyl triflate (74% yield).
출처 및 근거
- ORD 기록
- ord-3ca327c5cd5e4f5fa23064b8147e6a09
- 출처 데이터셋
- uspto-grants-2010_11
- 특허 번호
- US07825114B2
반응 노트
불러오는 중…