2,4-Dichloro-5-iodopyrimidine → HCID 178478336, 화합물

반응식

[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5](I)=[CH:4][N:3]=1.[NH:10]1[CH:14]=[C:13]([CH2:15][CH2:16][NH2:17])[N:12]=[CH:11]1.CC1(C)C(C)(C)OB([C:26]2[S:27][CH:28]=[CH:29][CH:30]=2)O1>>[Cl:1][C:2]1[N:7]=[C:6]([NH:17][CH2:16][CH2:15][C:13]2[N:12]=[CH:11][NH:10][CH:14]=2)[C:5]([C:26]2[S:27][CH:28]=[CH:29][CH:30]=2)=[CH:4][N:3]=1

참가 물질

반응물 3

HCID 2634382,4-Dichloro-5-iodopyrimidine

HCID 107036284,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane

HCID 178419017HCID 178419017, 화합물

생성물 1

HCID 178478336HCID 178478336, 화합물

실험 절차

Preparation according to procedures 2 and 3 with the use of 2,4-dichloro-5-iodo-pyrimidine, 2-(1H-imidazol-4-yl)-ethylamine and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

후처리

customPreparation

출처 및 근거

ORD 기록: ord-a85a65b957f24cebbd6b5a6c2df12e09
출처 데이터셋: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07825128B2

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