Thionyl Chloride → HCID 11694729, 화합물

반응식

S(Cl)([Cl:3])=O.[CH3:5][O:6][C:7]1[CH:8]=[C:9]([C:13]2[O:14][C:15]([CH3:20])=[C:16]([CH3:19])[N+:17]=2[O-])[CH:10]=[CH:11][CH:12]=1>>[ClH:3].[Cl:3][CH2:19][C:16]1[N:17]=[C:13]([C:9]2[CH:10]=[CH:11][CH:12]=[C:7]([O:6][CH3:5])[CH:8]=2)[O:14][C:15]=1[CH3:20]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 57718887HCID 57718887, 화합물

생성물 1

HCID 11694729HCID 11694729, 화합물

실험 절차

The entire toluenic solution from Example 1 (420 ml) was admixed at 60° C. dropwise with 54.2 g (0.456 mol) of thionyl chloride and stirred at <60° C. for up to 22 h. Subsequently, the mixture was concentrated by distilling off 229 ml. The suspension was cooled to <20° C., and the product was isolated by filtration with suction, washed 3 times with 20 ml each time of toluene and dried at elevated temperature under reduced pressure.

후처리

concentrationSubsequently, the mixture was concentrated
distillationby distilling off 229 ml
temperatureThe suspension was cooled to <20° C.
customthe product was isolated by filtration with suction
washwashed 3 times with 20 ml each time of toluene
customdried at elevated temperature under reduced pressure

출처 및 근거

ORD 기록: ord-ae8e13d121d746178669c1e74afa9872
출처 데이터셋: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07825144B2

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