Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzaldehyde → 2-Benzylidene-but-3-ynenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzaldehyde | HCID 240 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Malononitrile | HCID 8010 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 생성물 | 2-Benzylidene-but-3-ynenitrile | HCID 86030656 | — |
반응 단계
To a solution of benzaldehyde (2 g; 18.9 mmol) and malononitrile (1.37 g; 20.7 mmol) in ethanol (40 ml) was added 5 drops of piperidine and the mixture was heated at reflux overnight. The reaction was cooled, evaporated then purified by flash column chromatography eluting with 1:9 ethyl acetate/hexane and the product containing fractions combined and evaporated to give 930 mg of 2-benzylidene-but-3-yne nitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07825140B2 |
| 출처 데이터셋 | uspto-grants-2010_11 |
| ORD ID | ord-5a2abd7f645947b0b3ee9eb00a0bdf66 |
| 출처 메모 | uspto-grants-2010_11 |